Posted: 01/15/2016

New Developments in Diabetes Drugs

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There are an estimated 29 million people in the US living with diabetes, with most cases involving patients with type II diabetes according to the CDC. Individuals develop diabetes when the body is unable to produce or use insulin, a naturally occurring hormone that regulates blood sugar levels. The risk for diabetes increases when patients are overweight, physically inactive, and have a history of cardiovascular disease, high cholesterol, or family members with diabetes.

The management of type II diabetes can be difficult for some patients that have other conditions such as high blood pressure or obesity, which can complicate treatment options. One of the most difficult parts about treating patients with most diabetes medications available is that the effectiveness of such treatments relies on patient’s adherence to a healthy diet and exercise. However, new medications that combine two active ingredients are making it easier for patients with other related medical conditions to manage type II diabetes.

New Combination Diabetes Drugs

Glyxambi New Diabetes Medication
Some of the newest treatments available to treat type II diabetes contain a combination of two drugs that are designed help patients achieve glycemic control. Among one of the latest medications that combine two mechanisms of action to control type II diabetes is Glyxambi, an oral medication that contains empagliflozin and linagliptin. Empagliflozin belongs to a class of drugs called sodium glucose co-transporter-2 (SGLT2) inhibitors, which work by reducing the amount of glucose in the blood and absorption in the kidneys so that it is passed through urine. The other active ingredient in Glyxambi, linagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, works by inhibiting an enzyme, DPP-4, that inactivates a hormone in the gut called incretins. The incretins in the body causes the pancreas to produce more insulin and stops the liver from producing glucose. By inhibiting DPP-4 from breaking down incretins, Glyxambi helps regulate blood glucose levels to a normal range, especially after meals when type II diabetes patients require it the most.



Synjardy Newly Approved Diabetes Drug

Another new combination diabetes drug that came on the market in 2015 is called Synjardy. Synjardy is also a pill and contains a combination of empagliflozin (just like the SGLT2 inhibitor in Glyxambi) and metformin, a biguanide drug that has been prescribed alone or along with other diabetes medications for decades. Metformin works by suppressing glucose production in the liver while empagliflozin blocks the reabsorption of glucose into the bloodstream in the kidneys. Together these two medications have a more powerful effect on blood sugar levels.

If you are already taking more than one diabetes medication, ask your doctor about an oral combination drug like Glyxambi or Synjardy. These newer drugs can be more expensive, but the manufacturers often provide patient assistance that can significantly lower the monthly cost. Glyxambi is about $100 per month more expensive than Synjardy, but HelpRx offers a discount coupon for Glyxambi that can save you as much as 75% in local pharmacies. Search our site for discounts on the latest diabetes medications.

By HelpRx Staff Writer

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HelpRx.info is staffed by experts in the prescription medication industry. Get the latest health, medical news and pharmaceutical news that can save you money and allow you to take charge of your healthcare. With frequent updates about the prescription drug industry as well as medicine news, you'll gain an insider look into the industry and learn more about how to get the best price on your prescriptions while not sacrificing quality. Subscribe to the HelpRx.info pharmacy blog through our RSS feed or get updates by liking HelpRx.info on Facebook and following HelpRx.info on Twitter.

About HelpRx

Our discounts provide you access to negotiated prices on your prescription drugs at your local pharmacy. We can provide these because we're partnered with OptumRx, a BIG pharmacy benefit provider that provides prescription coverage for MILLIONS of people like you.

About ScriptRelief

Script Relief, the creator of the NPSN card and HelpRx discounts, helps consumers save an average of 50%, and up to 75%, off their prescriptions.

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Get your Prescription Discount Card and automatically SAVE on over 50,000 drugs nationwide.

Helprx_branded_card_desktop Click-here-redbg

Popular Post

 

About the HelpRx.info Blog

HelpRx.info is staffed by experts in the prescription medication industry. Get the latest health, medical news and pharmaceutical news that can save you money and allow you to take charge of your healthcare. With frequent updates about the prescription drug industry as well as medicine news, you'll gain an insider look into the industry and learn more about how to get the best price on your prescriptions while not sacrificing quality. Subscribe to the HelpRx.info pharmacy blog through our RSS feed or get updates by liking HelpRx.info on Facebook and following HelpRx.info on Twitter.

About HelpRx

Our discounts provide you access to negotiated prices on your prescription drugs at your local pharmacy. We can provide these because we're partnered with OptumRx, a BIG pharmacy benefit provider that provides prescription coverage for MILLIONS of people like you.

About ScriptRelief

Script Relief, the creator of the NPSN card and HelpRx discounts, helps consumers save an average of 50%, and up to 75%, off their prescriptions.

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About Our Savings:

HelpRx.info is a discount pharmacy service, partnered with a leading pharmacy benefit manager. We negotiate lower prices on prescription medications, that we pass on to our members for free. There is no cost to use our cards and coupon, and anyone can take advantage of our discounts, regardless of healthcare coverage.

Our savings assurance of “up to 75% off” comes from historical data from actual claims. This data includes savings for both brand name and generic medications.