This medicine is a beta blocker used to treat high blood pressure. It may also be used for other conditions as determined by your doctor.
Follow the directions for using this medicine provided by your doctor. SWALLOW WHOLE. Do not break, crush, or chew before swallowing. Take this medicine consistently on an empty stomach or consistently with food. Take this medicine at bedtime (about 10 p.m.), unless your doctor tells you otherwise. IF YOU ARE TAKING AN ANTACID WITH ALUMINUM IN IT, you may need to separate it by at least 2 hours from your dose of this medicine. Check with your pharmacist about how to take an antacid containing aluminum with this medicine. IT MAY TAKE 2-3 WEEKS TO RECEIVE THE FULL BENEFIT OF THIS MEDICINE. Do not suddenly stop taking this medicine. You may have an increased risk of side effects. If you need to stop this medicine or add a new medicine, your doctor will gradually lower your dose. STORE THIS MEDICINE at room temperature at 77 degrees F (25 degrees C) in a tightly-closed container, away from heat, moisture, and light. Brief storage between 59 and 86 degrees F (15 to 30 degrees C) is permitted. KEEP THIS MEDICINE out of the reach of children and away from pets. Take this medicine regularly to receive the most benefit from it. Taking this medicine at the same time each day will help you to remember. CONTINUE TO TAKE THIS MEDICINE even if you feel well. Do not miss any doses. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
WARNING: Do not suddenly stop taking this medicine. Sharp chest pain, irregular heartbeat, and, sometimes, heart attack may occur if you suddenly stop this medicine. The risk may be greater if you have certain types of heart disease. Your doctor should slowly lower your dose over several weeks if you need to stop taking this medicine. This should be done even if you only take this medicine for high blood pressure. Heart disease is common and you may not know you have it. Limit physical activity while you are lowering your dose. If new or worsened chest pain or other heart problems occur, contact your doctor right away. You may need to start taking this medicine again. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking mibefradil. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking other prescription and nonprescription medicines (eg, used for infections, inflammation, aches and pains, high blood pressure, heart problems, irregular heartbeat, diabetes, prostate problems, blood thinning, thyroid problems, depression, mental or mood problems, immune system suppression, allergic reactions, asthma, high cholesterol, seizures, local anesthesia, stomach or bowel problems, migraine headaches), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort). DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including Wolff-Parkinson-White syndrome, Down syndrome, Raynaud syndrome, an adrenal gland tumor (pheochromocytoma), allergies, pregnancy, or breast-feeding. Tell your doctor if you have a history of other heart problems (eg, angina, congestive heart failure, slow heartbeat), liver or kidney problems, blood vessel disease, lung or breathing problems (eg, chronic bronchitis, emphysema, chronic obstructive pulmonary disease / COPD), diabetes, low blood sugar, overactive thyroid, muscle problems, or glaucoma. Tell your doctor if you smoke or drink alcohol, if you will be having surgery, if you exercise, or if you have been fasting. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have asthma, uncontrolled heart failure, shock caused by serious heart problems, or very low blood pressure after a heart attack. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have moderate to severe heart block, sick sinus syndrome, or a very slow heartbeat and you do not have a permanent pacemaker. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
SIDE EFFECTS that may occur while taking this medicine include constipation, diarrhea, dizziness, drowsiness, fatigue, lightheadedness, nausea, stomach upset or cramping, trouble sleeping, vomiting, or weakness. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience chest pain; disorientation; fainting; fever with aching and sore throat; hallucinations; irregular heartbeat; memory loss; mental or mood changes (eg, depression); new or worsening muscle problems; numbness or tingling of the hands; red, swollen, blistered, or peeling skin; severe or persistent dizziness; shortness of breath or wheezing; sudden, unusual weight gain; swelling of the hands, ankles, or feet; unusual bruising; unusually slow heartbeat; very cold or blue fingers or toes; or vision changes. AN ALLERGIC REACTION TO THIS MEDICINE IS UNLIKELY, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; or swelling of the mouth, face, lips, or tongue. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include fainting; severe dizziness; shortness of breath; swelling of the hands, ankles, or feet; trouble breathing; very slow heart rate; or wheezing.
Reducing high blood pressure helps prevent strokes, heart attacks, and kidney problems. PATIENTS WHO TAKE MEDICINE FOR HIGH BLOOD PRESSURE often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop new symptoms. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out. CHECK WITH YOUR PHARMACIST about how to dispose of unused medicine.