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Patients with hypertension are at increased risk of both stroke and heart disease. High blood pressure affects not only these vital organs, but also every other part of the body. 95% of all cases of hypertension have no defined cause. However, there are known treatments to stop or slow its effects, and even to ... Read more

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Losartan Potassium Information:

Why is this medication prescribed?

Losartan is used alone or in combination with other medications to treat high blood pressure. Losartan is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart). Losartan may not decrease the risk of stroke in African Americans who have these conditions. This medication is also used to treat kidney disease in people who have type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) and high blood pressure. Losartan is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

How should this medicine be used?

Losartan comes as a tablet to take by mouth. It is usually taken once or twice a day with or without food. To help you remember to take losartan, take it at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take losartan exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of losartan and gradually increase your dose.

If your child can not swallow a tablet, talk to your doctor or pharmacist. The pharmacist can prepare a liquid form of this medication for your child.

Losartan controls high blood pressure but does not cure it. Your blood pressure may decrease during the first week of your treatment, but it may take 3-6 weeks for you to notice the full benefit of losartan. Continue to take losartan even if you feel well. Do not stop taking losartan without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Other uses for this medicine

Losartan is also sometimes used to treat congestive heart failure (condition in which the heart is unable to pump enough blood to the rest of the body). Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking losartan,

  • tell your doctor and pharmacist if you are allergic to losartan, any other medications, or any of the ingredients in losartan tablets. Ask your pharmacist for a list of the ingredients.
  • tell your doctor if you have diabetes (high blood sugar) and you are taking aliskiren (Tekturna, in Amturnide, Tekamlo, Tekturna HCT). Your doctor will probably tell you not to take losartan if you have diabetes and you are also taking aliskiren.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), and selective COX-2 inhibitors such as celecoxib (Celebrex); diuretics ('water pills') including potassium-sparing diuretics such as amiloride (Midamor, in Hydroride, in Moduretic), spironolactone (Aldactone, in Aldactazide), and triamterene (Dyrenium, in Dyazide, in Maxzide); fluconazole (Diflucan); lithium (Eskalith CR, Eskalith, Lithobid); phenobarbital; potassium supplements; and rifampin (Rifadin, Rimactane). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had heart failure or kidney or liver disease.
  • tell your doctor if you are breast-feeding.
  • you should know that losartan may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking losartan. To help avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
  • you should know that diarrhea, vomiting, not drinking enough fluids, and sweating a lot can cause a drop in blood pressure, which may cause lightheadedness and fainting. Tell your doctor if you have any of these problems or develop them during your treatment.

What special dietary instructions should I follow?

Do not use salt substitutes containing potassium without talking to your doctor. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Losartan may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dizziness
  • leg, knee, or back pain
  • muscle cramps or weakness
  • diarrhea
  • heartburn
  • decreased sensitivity to touch

Some side effects can be serious. If you experience any of these symptoms or those listed in the SPECIAL PRECAUTIONS section, call your doctor immediately:

  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness
  • difficulty breathing or swallowing
  • chest pain

Losartan may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat, light, and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include the following:

  • dizziness
  • fainting
  • fast or slow heartbeat

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly to determine your response to losartan.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

  • Cozaar®

What is Losartan Potassium?

Losartan Potassium is an antihypertensive agent that is used to reduce the risk of stroke and left ventricular hypertrophy in patients with high blood pressure. Results of taking Losartan Potassium are often seen after only a week on the medication, though full potency may not be reached until 3 to 6 weeks. It has also had success in slowing the progression of diabetic kidney disease in patients with type 2 diabetes.

How do I take Losartan Potassium?

Losartan Potassium can be taken by itself or in conjunction with other antihypertensive agents, and may be taken with or without food. It can be taken either once or twice daily as prescribed by a doctor. It comes as a pill or as a liquid to be taken orally. Take your medication with a full glass of water at regular intervals.

Before taking, tell your doctor if:

  • You are pregnant or planning to become pregnant
  • You are breast-feeding
  • You have stomach problems such as vomiting or diarrhea
  • You have liver problems
  • You have kidney problems
  • You are taking any other medications, especially NSAIDs and other medication to reduce blood pressure
  • You are taking any supplements, especially vitamins containing potassium and water pills

What are the possible side effects of taking Losartan Potassium?

It is not known whether losartan potassium is transferred into breast milk so discuss it with your doctor if you are breast-feeding prior to beginning usage.  Losartan potassium is known to cause birth defects, so do not take it if you are pregnant.  Some people experience allergic reaction while taking losartan potassium, so contact a medical professional if you experience redness or swelling of the lips, eyes, or face.  Losartan potassium can worsen kidney problems in those with irregular kidney functioning, so contact your doctor if you notice swelling or pain in the ankles or other joints.  Common side effects include upper respiratory infections, dizziness, and back pain.

What if I forget to take a dose of Losartan Potassium?

If you forget to take a dose of losartan potassium take the missed dose as soon as you remember.  If it is close to your next scheduled dose, skip the missed dose and resume your regular dosage schedule.  Do not take a double dose of losartan potassium.

How do I store losartan potassium?

Store losartan potassium at room temperature in an air-tight container that protects the medication from light.  Keep losartan potassium and all other medications out of reach of children and pets.

What happens if I overdose on losartan potassium?

If you overdose on losartan potassium, contact the emergency poison control center immediately.  The most likely symptom of overdose is hypotension.  Hypotension is abnormally low blood pressure, which is often felt as dizziness or faintness.


Do not take losartan potassium if you are pregnant or planning to become pregnant.  If you become pregnant while taking losartan potassium, contact your doctor immediately and stop taking the medication as soon as safely possible.  If you are being treated with diuretics, the ingestion of losartan potassium can create hypertensive effects.  Patients with severe congestive heart failure may be at increased risk of renal failure while taking this medication.

Brand Names

Losartan potassium is a generic drug. Brand names include Cozaar.

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