This medicine is a phosphodiesterase type 3 inhibitor used to reduce the symptoms of intermittent claudication (pain, cramping, numbness, or weakness in the legs) that may occur with walking. It may also be used to treat other conditions as determined by your doctor.
Follow the directions for using this medicine provided by your doctor. AN ADDITIONAL PATIENT INFORMATION LEAFLET is available with this medicine. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. Take this medicine at least 30 minutes before or 2 hours after eating. CHECK WITH YOUR DOCTOR before you eat grapefruit or drink grapefruit juice while you use this medicine. THE EFFECTS OF THIS MEDICINE ARE NOT IMMEDIATE. Although you may experience the benefits of this medicine 2 to 4 weeks after beginning treatment, treatment for up to 12 weeks may be necessary before this medicine takes effect. Do NOT stop taking this medicine or change your dose without checking with your doctor. STORE THIS MEDICINE at room temperature between 68 and 77 degrees F (20 and 25 degrees C) in a tightly-closed container, away from heat, moisture, and light. KEEP THIS MEDICINE out of the reach of children and away from pets. This medicine works best if it is used at the same time(s) each day. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once. If more than one dose is missed, contact your doctor or pharmacist.
WARNING: Medicines similar to this medicine have shortened the lives of people with certain types of heart failure. Do not use this medicine if you have any type of heart failure. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking antiplatelet medicines (eg, clopidogrel), certain azole antifungals (eg, ketoconazole), diltiazem, esomeprazole, certain macrolide antibiotics (eg, erythromycin), nefazodone, omeprazole, protease inhibitors (eg, boceprevir, ritonavir), certain selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine, fluvoxamine, sertraline), or telithromycin. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including liver or kidney problems, low blood platelet levels, allergies, pregnancy, or breast-feeding. Tell your doctor if you have recently had surgery or any type of bleeding. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have heart failure, bleeding problems or a disorder that cause the inability to form blood clots, or active bleeding (eg, bleeding peptic ulcer, bleeding in the brain). Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
SIDE EFFECTS that may occur while taking this medicine include abnormal stools, back pain, diarrhea, dizziness, gas, headache, increased cough, indigestion, light-headedness, mild sore throat, muscle aches, nausea, runny nose, or stomach pain. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience black, tarry stools; chest, jaw, or left arm pain; confusion; fainting; fast or irregular heartbeat; fever, chills, or persistent cough or sore throat; one-sided weakness; numbness of an arm or leg; red, swollen, blistered, or peeling skin; shortness of breath; slurred speech; sudden, severe headache or vomiting; severe or persistent dizziness or light-headedness; sudden, unusual weight gain; swelling of the hands, ankles, or feet; unusual bruising or bleeding; vision changes (eg, blindness, double vision); or vomiting material that looks like coffee grounds. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; or swelling of the mouth, face, lips, or tongue. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
IF OVERDOSE IS SUSPECTED, contact your local poison control center or emergency room immediately. Symptoms of overdose may include diarrhea; fainting; fast or irregular heartbeat; or severe headache, dizziness, or light-headedness.
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. IF YOU WILL BE USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, be sure to obtain necessary refills before your supply runs out. CHECK WITH YOUR PHARMACIST about how to dispose of unused medicine.