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Treximet Coupon & Discounts

Save on Treximet at your pharmacy with the free discount below.

Treximet is prescribed to help treat the conditions and symptoms that accompany migraine headaches. However, it can only treat a headache that has begun, and cannot prevent a migraine from occurring nor reduce the number of migraine attacks. Because ten tablets of Treximet cost between $800 and $900, this medic ... Read more

Treximet Discount

Savings with HelpRx discount up to:

75% Off

on Treximet

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*The discount percent is an estimate based off recent cardholder data. Valid as of May 22, 2018

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Treximet Information:

What is Treximet?

Treximet is a combination of two medications - sumatriptan and naproxen - each performing a different role in treating migraine headaches. Sumatriptan is a selective serotonin receptor agonist (SSRA) that blocks pain and pain signals by narrowing blood vessels. It also prevents the release of the substances that cause the nausea, pain, and other symptoms of migraines. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) that reduces the presence of hormones that cause inflammation and pain.

How do I take Treximet?

Treximet is a tablet that is taken at the first signs of a migraine or after the migraine has started (it will not prevent the onset of a migraine). If one tablet does not provide relief, a second may be taken, but no sooner than two hours after the first one. Only two doses of the Treximet drug can be taken in a twenty-four hour period.

Before taking Treximet, tell your doctor if:

  • You are allergic to sumatriptan, naproxen, or any of the ingredients in the Treximet tablet
  • You are pregnant, planning a pregnancy, or are nursing a child
  • You are taking any medications (both prescription and non-prescription), vitamins, or nutritional supplements
  • You have liver disease
  • You have hypertension
  • You have asthma
  • You have liver or kidney disease
  • You have epilepsy or have seizures
  • You have ulcerative colitis or other intestinal diseases or conditions
  • You have, or have had, angina, heart disease, a stroke or heart attack, heart surgery, or problems with blood circulation
  • You are taking anti-depressants
  • You are taking MAO inhibitors
  • You are taking almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, or zolmitriptan
  • You are taking ergot medications

What are the possible side effects of taking Treximet?

Some who have taken Treximet have reported a range of side effects of varying degrees of severity. Less severe side effects include constipation, nausea, drowsiness, tight muscles, dizziness, flushing of the face, or a feeling of heaviness in parts of the body.

Severe side effects requiring immediate medical attention include bloody or tarry stools, coughing or vomiting blood, pain in the upper stomach, symptoms of an allergic reaction, changes in urine color, symptoms of jaundice, sudden vision changes, slurred speech, loss of balance, chest pain, sudden weight gain, seizures or convulsions, tachycardia, arrhythmia, or fainting. This list is not exhaustive; if any unusual symptoms are experienced while taking Treximet, contact your healthcare provider immediately.

What if I forget to take a dose of Treximet?

Because Treximet is taken only on an as needed basis, once a migraine headache has begun, it is unlikely that a dosage can be missed. However, if the first dose does not relieve symptoms, do not take a second dose until at least two hours have passed. Do not take more than two doses in a twenty-four hour period.

How do I store Treximet?

Keep Treximet tightly sealed in its original container and out of the reach of children, and store it in an area that is free from high humidity and extremes of temperature. Unused or expired doses should be disposed of according to the instructions of your local pharmacist.

What happens if I overdose on Treximet?

If an overdose of the Treximet drug has been taken, contact Poison Control at 1-800-222-1222. If the individual has lost consciousness or stopped breathing, contact Emergency Services at 911.


Contact your physician if you become pregnant while taking Treximet. Do not drink alcohol while taking this medication. Do not drive, use heavy machinery, or use power tools until you know how your body reacts to Treximet. Do not use this medication for headaches other than migraines. This medication may cause stroke, myocardial infarction, or other cardiovascular problems. Treximet may cause gastrointestinal problems, including ulcers and bleeding.

Brand Names

Treximet is a proprietary formulation of sumatriptan and naproxen and is available only under the brand name. As such, the Treximet coupon at HelpRx is designed to assist those who do not have a Treximet copay card by keeping the cost of Treximet affordable. Download one and use it to lower the price of Treximet by up to 75% when filling a prescription.

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Treximet Information:

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About Our Savings: is a discount pharmacy service, partnered with a leading pharmacy benefit manager. We negotiate lower prices on prescription medications, that we pass on to our members for free. There is no cost to use our cards and coupon, and anyone can take advantage of our discounts, regardless of healthcare coverage.

Our savings assurance of “up to 75% off” comes from historical data from actual claims. This data includes savings for both brand name and generic medications.