This medicine is a calcium channel blocker. This medicine is used for treating supraventricular tachycardia, a rhythm disturbance of the heart. It is also used for controlling heart rate response to other rhythm disturbances, specifically atrial fibrillation and atrial flutter. It may also be used for other conditions as determined by your doctor.
Follow the directions for taking this medicine provided by your doctor. This medicine is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using this medicine at home, a health care provider will teach you how to use it. Be sure you understand how to use this medicine. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions. Do NOT use this medicine if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged. STORE THE UNDILUTED SOLUTION OF THIS MEDICINE at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Because the product does not contain a preservative, any unused portion should be discarded. This medicine is stable for 24 hours when added to compatible intravenous (IV) solutions at 77 degrees F (25 degrees C). Protect from heat, light, and moisture. KEEP THIS MEDICINE, as well as syringes and needles, out of reach of children and pets. IF YOU MISS A DOSE of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
SOME MEDICINES MAY INTERACT with this medicine. DO NOT TAKE THIS MEDICINE if you are taking dofetilide, or you have taken disopyramide within the past 48 hours. TELL YOUR HEALTHCARE PROVIDER if you are taking any other medicines, especially any of the following: beta-blockers (eg, propranolol), clonidine, disopyramide, ketolides (eg, telithromycin), macrolides (eg, erythromycin), ritonavir, phenobarbital, rifampin, St. John's wort, aldosterone blockers (eg, eplerenone), aspirin, carbamazepine, colchicine, cyclosporine, digoxin, doxorubicin, dronedarone, eletriptan, everolimus, flecainide, HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), lithium, narcotic pain relievers (eg, fentanyl), paclitaxel, quinazolines (eg, terazosin), quinidine, ranolazine, theophyllines, tolvaptan, or other blood pressure medicines (eg, lisinopril). This may not be a complete list of all interactions that may occur. Ask your health care provider if this medicine may interact with other medicines you take. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including heart failure or other heart problems (eg, a very slow heart rate, heart block, heart valve disease), low blood pressure, kidney or liver problems, muscular dystrophy, a neuromuscular disease, allergies, pregnancy, or breast-feeding. Tell your doctor if you have had a recent heart attack with lung congestion or you are being treated for cancer. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have certain heart problems (eg, left ventricular dysfunction, sick sinus syndrome, second- or third-degree heart block and do not have a pacemaker); very low blood pressure; moderate to severe congestive heart failure (CHF); atrial fibrillation or flutter and a pre-excitation syndrome (extra conduction pathway in the heart), such as Wolff-Parkinson-White (WPW) syndrome or Lown-Ganong-Levine (LGL) syndrome; or shock due to serious heart problems. This medicine should not be used in CHILDREN; safety and effectiveness in these children have not been confirmed. Contact your doctor or pharmacist if you have any questions or concerns about using this medicine.
SIDE EFFECTS that may occur while taking this medicine include: dizziness; fatigue; headache; lightheadedness; mild pain, redness, or swelling at the injection site. If they continue or are bothersome, check with your doctor. SEEK MEDICAL ATTENTION RIGHT AWAY if any of these SEVERE side effects occur: chest pain; fainting; lightheadedness, especially when standing; severe dizziness; shortness of breath; swelling of the feet or hands; symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine, pale stools, severe or persistent stomach pain, fever, general feeling of being unwell); unusually fast, slow, or irregular heartbeat. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
IF OVERDOSE IS SUSPECTED, contact your local poison control center or emergency room immediately. Symptoms may include decreased mental status; dizziness; loss of consciousness; shortness of breath; slow or irregular heartbeat.
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. Do NOT reuse needles, syringes, or other materials. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when it is full.