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Zonisamide Coupon & Discounts

Save on Zonisamide at your pharmacy with the free discount below.

Zonisamide may be used alongside other medications to prevent and control partial onset seizures in people with epilepsy. This medication comes as a capsule and is available in 25mg, 50mg, and 100mg strengths. The zonisamide price usually starts around $25 for sixty 25mg capsules and may be $100 or more for the ... Read more

Zonisamide Discount

Savings with HelpRx discount up to:

33% Off

on Zonisamide

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*The discount percent is an estimate based off recent cardholder data. Valid as of May 21, 2018

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Zonisamide Information:

What is zonisamide?

Zonisamide is an anticonvulsant drug. Its mechanism of action is not fully understood, but when used alongside other medications as adjunctive therapy, it can help prevent seizures in adults with epilepsy.  

How do I take zonisamide?

Take the zonisamide drug only as frequently as your doctor has told you to (usually twice a day). Swallow the capsule whole, and drink a full glass of water to prevent kidney stones from forming. You may take this medication with or without food. Try to use zonisamide at the same times every day in order to keep the level of medicine in your body at a consistent level.

Before taking zonisamide, tell your doctor if:

  • You are allergic to this or any other medications
  • You are taking any other prescription or non-prescription drugs or supplements
  • You have a history of liver or kidney disease
  • You have a history of mental disorders
  • You have a history of metabolic acidosis (an imbalance of acid in the blood)
  • You are currently or have ever been on a low-carbohydrate, high-protein diet
  • You have any medical conditions that affect your breathing
  • You have ongoing diarrhea due to an illness
  • You have a bone or growth disorder
  • You are breastfeeding, pregnant, or trying to become pregnant

What are the possible side effects of taking zonisamide?

Some of the most common side effects of zonisamide are drowsiness, dizziness, difficulty sleeping, temporary loss of coordination, loss of appetite, and diarrhea. If you experience any side effects that last a long time or become bothersome, tell your doctor. In rare cases, zonisamide may cause an imbalance of acid in your blood (metabolic acidosis), which can lead to a fast heart rate, rapid breathing, severe fatigue, and bone pain. Get emergency medical attention right away if you notice any of these warning signs. This is not a complete list of all possible side effects; contact your doctor right away if you have any other side effects that concern you, or if your seizures become worse or more frequent.

What happens if I forget to take zonisamide?

Take the forgotten dose as soon as you remember, unless it is almost time for your next scheduled dose. Skip the missed dose if this is the case. Never double your dose of zonisamide to catch up. 

How do I store zonisamide?

Store zonisamide at room temperature. Do not keep it in the bathroom, as light and humidity can negatively affect this medicine. As with all prescription drugs, you should keep zonisamide out of reach of pets and children. Talk to your pharmacist about how to safely dispose of any expired or unused capsules.

What happens if I overdose on zonisamide?

Overdosing on the zonisamide drug can be very dangerous and may cause shallow breathing, extreme dizziness, and fainting. If you or someone in your household has overdosed, call Poison Control at 1-800-222-1222 right away. If the person who overdosed has lost consciousness, get emergency medical help.


Zonisamide may make you sweat less, which puts you at greater risk for heat stroke. Be careful not to overexert yourself in hot weather while taking this medication. Do not drink alcoholic beverages while taking this drug, since alcohol increases the risk for certain side effects. Do not drive or operate heavy machinery until you know how the zonisamide drug affects you.


Brand Name

Zonisamide is also available under the brand name Zonegran. As a generic, zonisamide is usually less expensive, and you can reduce the cost even further with a coupon from HelpRx.

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“The price for my prescription has gone up the past year and paying the out of pocket cost was getting increasingly difficult. Now, through HelpRx I’ve saved hundreds! Thank you HelpRx” - Janet Larsen - Austin, TX

Zonisamide Information:

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About Our Savings: is a discount pharmacy service, partnered with a leading pharmacy benefit manager. We negotiate lower prices on prescription medications, that we pass on to our members for free. There is no cost to use our cards and coupon, and anyone can take advantage of our discounts, regardless of healthcare coverage.

Our savings assurance of “up to 75% off” comes from historical data from actual claims. This data includes savings for both brand name and generic medications.