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Ofloxacin Information:
What is ofloxacin?
Ofloxacin is a quinolone antibiotic that is made up of a mixture of both levofloxacin and dextrofloxacin. It is used to treat a variety of infections, especially those caused by pathogens that actually enter individual cells. It is commonly prescribed for infections of the urethra, urinary tract, cervix, and prostate, and for certain types of pneumonia and bronchitis. Ofloxacin is also used in drops to treat eye and ear infections. It works by inhibiting bacterial DNA gyrase, an enzyme that is used when DNA is separating for cell division. This stops the growth and reproduction of the bacteria. Ofloxacin and other quinolone antibiotics usually do not affect mammalian cells in small doses. However, high doses of quinolones have been shown to affect fibroblast cells and lymphocytes, and they have been shown to harm and affect the growth of eukaryotic cells. Some bacteria have shown resistance to ofloxacin, especially those that cause STDs. Talk to your doctor about the risks and benefits of this medication.
How do I take ofloxacin?
The amount of time you take ofloxacin will depend on the severity of your infection. Follow your doctor’s instructions. Ofloxacin tablets should be taken orally with a glass of water. Take your medication at easily spaced intervals, and do not stop taking it until you have finished the full course prescribed by your doctor. Drink lots of water while taking ofloxacin.
To use ofloxacin ear drops, warm the bottle in your hands for a few minutes. Then lie down with the affected ear facing upward. Place the prescribed number of drops in the ear and avoid touching the dropper to your ear, hands, or any other surface. If you have an inner ear infection, press the lower ear cartilage upward a few times to push the solution into the inner ear. Wash your hands if any medication gets on your fingers.
To use ofloxacin eye drops, wash your hands and shake the bottle to mix the medication. Then, tilt your head back and pull down your lower eyelid to form a pocket. Drop one drop of the solution into the pocket of your lid. Avoid touching your eye or lid with the dropper. Close your eyes for 2-3 minutes without blinking or squeezing your eye shut and apply slight pressure to your tear duct with one of your fingers to allow the medication to be absorbed by your eye. If you were prescribed two drops, wait about five minutes before applying the next one. Wash any medication off your hands after using.
Before taking ofloxacin, tell your doctor if:
- You have had a bad reaction to quinolone antibiotics.
- You have kidney or liver disease.
- You are pregnant or breast-feeding.
- You have experienced seizures.
- You have a history of arthritis or joint and tendon problems.
- You have a cerebral disorder or a disorder of the central nervous system.
- You have an irregular heartbeat.
- You have myasthenia gravis.
- You are allergic to any of the ingredients in this medication.
- You have arteriosclerosis, or hardened arteries.
- You are taking prescription or nonprescription drugs, vitamins, or supplements, especially NSAIDs, supplements like calcium, magnesium, and aluminum; antacids and medications for GERD, HIV medications, cyclosporine, theophylline, warafin, and probenecid.
What are the possible side effects of taking ofloxacin?
Side effects from taking ofloxacin include diarrhea, nausea, headache, indigestion, vaginal irritation, vomiting, and trouble sleeping. Serious but rare side effects include seizures, joint or tendon pain and swelling, tremors, breathing problems, chest pain, severe headache, blistering of the skin, confusion, hallucinations, or mental changes. If you experience any of these serious side effects, stop your medication and contact your doctor at once. If you experience any other strange or severe side effects, report them to your doctor immediately. See the warnings section for more information.
What if I forget to take a dose of ofloxacin?
If you miss a dose of ofloxacin, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue on your regular schedule. Do not take a double dose of ofloxacin to make up for a missed one. Finish all doses your doctor has prescribed to treat your infection in order to prevent bacterial resistance and relapse.
How do I store ofloxacin?
Store ofloxacin tightly closed in its original container at a room temperature between 59 and 86 degrees Fahrenheit. Keep your medication out of reach of children and pets, and throw out any expired medication.
What happens if I overdose on ofloxacin?
Signs of overdose on ofloxacin may include dizziness, drowsiness, nausea, confusion, hot and cold flashes, and slurred speech. If you or someone you know has overdosed on ofloxacin, contact the Poison Control Center at 1-800-222-1222 or call 911.
Warnings
Ofloxacin and other fluoroquinolone antibiotics have been known to cause tendonitis and spontaneous tendon ruptures. This is especially risky in the elderly. Ofloxacin can also cause toxic psychosis and seizures. This medication is not FDA approved for children under age 18 and should be used with caution in the elderly.
Brand Names
Brand names for ofloxacin include Floxin and Ocuflox. Search our site for free coupons to save up to 29% off the ofloxacin retail price. Also search for brand-name ofloxacin products and get up to 50-80% off the pharmacy cost.
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