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Actoplus Met Coupon & Discounts

Save on Actoplus Met at your pharmacy with the free discount below.

Actoplus Met is a drug used in the treatment of Type 2 diabetes; it is dispensed as a tablet in dosage strengths of 15mg/500mg and 15mg/850mg (pioglitazone/metformin, the drugs found in this medication). The Actoplus Met price for a supply of sixty tablets ranges from $537 to $618, depending on strength. At Hel ... Read more

Actoplus Met Discount

Savings with HelpRx discount up to:

75% Off

on Actoplus Met

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*The discount percent is an estimate based off recent cardholder data. Valid as of May 22, 2018

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Actoplus Met Information:

What is Actoplus Met?

Actoplus Met is a combination of two oral diabetes medications, pioglitazone and metformin, prescribed to treat Type 2 diabetes. Along with diet and exercise, it helps control blood sugar levels. Pioglitazone, a thiazolidinedione, increases the body’s sensitivity to insulin, aiding in its use; metformin, a biguanide, helps decrease glucose absorption and increases the response to insulin. This medication is not used to treat Type 1 diabetes.

How do I take Actoplus Met?

Actoplus Met is administered as a coated tablet that is taken orally once or twice a day, with food, depending on the dosage strength and requirements of the prescription. Dosing frequency will vary by patients according to their medical profile. Take this medication only as directed. Swallow the tablet whole; do not crush, split, or chew the tablet.

Before taking Actoplus Met, tell your doctor if:

  • You are allergic to pioglitazone, metformin, or any of the ingredients in the Actoplus Met drug
  • You are pregnant, planning a pregnancy, or are nursing a child
  • You are taking any prescription or non-prescription medications, vitamins, or supplements
  • You are taking insulin or other medications to treat diabetes
  • You are taking ACE inhibitors, medication to treat hypertension, hormonal contraceptives, beta-blockers, calcium channel blockers, diuretics, hormone replacement therapy, medications for asthma, mental illness, or thyroid disease, nausea medications, or oral steroids
  • You are taking atorvastatin, gemfibrozil, ketoconazole, midazolam, nifedipine, rifampin, acetazolamide, amiloride, digoxin, furosemide, isoniazid, morphine, niacin, phenytoin, procainamide, quinidine, quinine, ranitidine, topiramate, triamterene, trimethoprim, vancomycin, or zonisamide
  • You have, or have had, a heart attack, stroke, congestive heart failure, diabetic ketoacidosis, bladder cancer, high cholesterol or triglyceride levels, coronary heart disease, arrhythmia, or sleep apnea
  • You have, or have had, kidney or liver disease, diabetic eye disease, a serious infection, severe diarrhea, or severe vomiting
  • You are being treated for mental illness
  • You eat less or exercise more frequently than normal

What are the possible side effects of taking Actoplus Met?

Some individuals have reported side effects after taking the Actoplus Met drug. Mild symptoms include bloating, constipation, diarrhea, flushed skin, gas, headache, heartburn, indigestion, muscle pain, changes to nails, pain in the arms or legs, sore throat, stomach pain, or a metallic taste in the mouth. If any of these conditions persist or worsen, contact your healthcare provider.

Severe side effects requiring immediate medical attention include signs of an allergic reaction (swelling of the face, mouth, lips, throat, or tongue; hives, rash, or itching; difficulty breathing or swallowing), chest pain, abdominal or back pain, vision changes or loss, symptoms of jaundice, problems with urination, changes in urine color, or bloody urine.

What if I forget to take a dose of Actoplus Met?

If you forget to take a scheduled dose of Actoplus Met, do so as soon as you remember and are able to take it with food. If it is almost time for the next scheduled dose, however, skip the one missed and resume the regular dosing schedule. Do increase the number of pills taken or change the dosing regimen to make up for a missed dose. 

How do I store Actoplus Met?

Keep Actoplus Met tightly sealed in its original container, out of the reach of children and away from the extremes of temperature and humidity. Dispose of any unused or expired doses according to the instructions of a pharmacist.

What happens if I overdose on Actoplus Met?

If an overdose of Actoplus Met is suspected, contact the Poison Control Center at 1-800-222-1222. If the individual has stopped breathing or lost consciousness, contact Emergency Services at 911. Symptoms of an overdose include tachycardia or bradycardia, appetite loss, rapid breathing, symptoms of jaundice, general discomfort or weakness, dizziness, extreme fatigue, chills, lightheadedness, nausea, or vomiting.


Do not drink alcohol while taking Actoplus Met. This medication may cause lactic acidosis, liver problems, bladder cancer, or congestive heart failure. Contact your doctor if you become pregnant while taking this drug. Actoplus Met may increase the risk of bone fractures in women. Wear a diabetic identification bracelet to ensure proper treatment in an emergency.

Brand Names

Actoplus Met is the brand name of a combination of the diabetes medications pioglitazone and metformin; it is also available as Actoplus Met XR, but the formulation is somewhat different and one should not be substituted for the other without a doctor’s permission. To help with controlling the Actoplus Met price, a coupon can be downloaded from this page to help lower prices by as much as 75% in pharmacies nationwide. 

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Actoplus Met Information:

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About Our Savings: is a discount pharmacy service, partnered with a leading pharmacy benefit manager. We negotiate lower prices on prescription medications, that we pass on to our members for free. There is no cost to use our cards and coupon, and anyone can take advantage of our discounts, regardless of healthcare coverage.

Our savings assurance of “up to 75% off” comes from historical data from actual claims. This data includes savings for both brand name and generic medications.