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Refissa Coupon & Discounts

Save on Refissa at your pharmacy with the free discount below.

Refissa is a topical retinoid medication used to treat acne vulgaris. It comes in .02% and 0.05% strengths. Refissa costs around $200 per tube, which is considerably less than brands such as Retin-A, but still expensive. If your insurance doesn’t cover dermatology, our discount coupons are a big help. Cli ... Read more

Refissa Discount

Savings with HelpRx discount up to:

75% Off

on Refissa

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*The discount percent is an estimate based off recent cardholder data. Valid as of May 23, 2018

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Refissa Information:

What is Refissa?

Refissa contains tretinoin, a retinoid medication which is a derivative of vitamin A. Refissa is most often prescribed to treat acne vulgaris, but some also use tretinoin as an anti-wrinkle treatment. It works by acting on retinoid acid receptors which affects protein synthesis and epithelial cell growth which increases skin cell turnover and unclogs pores. Some studies also reveal that it boosts collagen retention and production.

How do I use Refissa?

Refissa cream is usually applied once every two or three days at bedtime. This medication should not be applied more than once per day. Your doctor or dermatologist will recommend your course of treatment. Before using Refissa, wash your face and neck with a gentle cleanser and allow it to dry completely. Use enough medication to lightly cover the affected areas. A pea-sized amount for each side of the face should be sufficient. Keep this medication away from your eyes, nostrils and mouth. If you have doubts about how much you should apply, talk to your doctor or pharmacist.

Before taking Refissa, tell your doctor if:

• You are pregnant, plan to become pregnant, or you are breastfeeding.
• You are taking any vitamins or prescription or non-prescription medications.
• You are currently using any other skin products on the affected areas.
• You are allergic to any of the ingredients in Refissa.
• You have had severe or bothersome reactions to other skin products.

What are the possible side effects of using Refissa?

Refissa may cause your skin to peel. Your skin may also become red and irritated. These side effect tend to lessen over time. Your acne may become worse before it gets better. Some may also experience a lightening or darkening of the skin. If you see blistering, swelling or crusting on or near the areas you are applying your medication, stop using Refissa and tell your doctor as soon as possible. If you experience any unusual side effects or if your acne does not get better after 2 months, report this to your doctor as well.

What if I forget to take a dose of Refissa?

If you use Refissa every day and you miss a dose, skip the missed dose and continue on your regular routine. Do not apply Refissa more than once a day. If you use Refissa every 2 or 3 days, apply the missed dose on the evening that you remember and then continue on your regular schedule. 

How do I store Refissa?

Store Refissa in the tube it comes in at a room temperature less than 86 degrees Fahrenheit. Keep the tube tightly closed and keep it out of reach of children and pets.

What happens if I overdose on Refissa?

Overuse of Refissa can result in exaggerated side effects, such as severely scaly skin, pain and irritation. If you think you are using too much of this medication, talk to your doctor about changing your dose and make sure you are applying the right amount. If someone accidentally ingests this medication, contact the Poison Control Center at 1-800-222-1222.


Stay out of the sun and away from sun lamps and tanning beds while using Refissa. This product causes your skin to be more sensitive to the sun’s rays. Ask your doctor if it is ok to use any other skincare products that you are using or want to use while using Refissa. This medication is for topical use only. Do not swallow or use near the eyes, nose or mouth.

Brand Names

The generic name of Refissa is tretinoin. There are many other brand names for this medication including Renova, Atralin and Retin A, and there are similar drugs such as adapalene and Differin. Search our site for coupons for Refissa and any of these other retinoid medications and find the most affordable drug for you.

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Refissa Information:

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About Our Savings: is a discount pharmacy service, partnered with a leading pharmacy benefit manager. We negotiate lower prices on prescription medications, that we pass on to our members for free. There is no cost to use our cards and coupon, and anyone can take advantage of our discounts, regardless of healthcare coverage.

Our savings assurance of “up to 75% off” comes from historical data from actual claims. This data includes savings for both brand name and generic medications.